Development

Scientific notes of Pavlov. Scientific notes. Possibilities of autofluorescence dermatoscopy for assessing age-related

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ON THE. ..."

ST. PETERSBURG

STATE MEDICAL UNIVERSITY

them. acad. I. P. PAVLOVA

SCIENTISTS

NOTES

St. Petersburg State

“SCIENTIFIC NOTES of St. Petersburg State Medical University named after. acad. I. P. Pavlova

Medical University named after. acad. I. P. Pavlova

N. A. YAITSKY

Volume XVI · 2 · 2009

PUBLISHING HOUSE SPbSMU

E.K. Ailamazyan – academician. RAMS (St. Petersburg) Editor-in-chief – S. H. Al Shukri – prof. (St. Petersburg) N. A. Yaitsky – academician. RAMS Yu. S. Astakhov – prof. (St. Petersburg) Deputy. editor-in-chief – V.L. Bykov – prof. (St. Petersburg) E. V. Sokolovsky – Doctor of Medical Sciences, Prof.

A. A. Vorobyov - academician. RAMS (Moscow) Responsible Secretary - G.I. Vorobyov - academician. RAMS (Moscow) L. A. Aleksina – Doctor of Medical Sciences, Prof.

A. M. Dygai – prof. (Tomsk) B.V. Afanasyev – doctor of medical sciences, prof. N.V. Kornilov – member. corr. RAMS (St. Petersburg) R. V. Babakhanyan – Doctor of Medical Sciences, Prof. M. T. Lutsenko – prof. (Blagoveshchensk) E. R. Barantsevich – Doctor of Medical Sciences, Prof. L. V. Potashov – member. corr. RAMS (St. Petersburg) A. P. Bobrov – Doctor of Medical Sciences, Prof. M. R. Sapin - academician. RAMS (Moscow) N. I. Vishnyakov – Doctor of Medical Sciences, Prof. V. M. Sedov – prof. (St. Petersburg) A. Ya. Grinenko – Doctor of Medical Sciences, Prof. S. B. Seredenin – academician. RAMS (Moscow) A. A. Skoromets – academician. RAMS (St. Petersburg) V. V. Gritsenko – Doctor of Medical Sciences, Prof.

M. M. Soloviev – prof. (St. Petersburg) Yu. D. Ignatov – academician. RAMS A. S. Tiganov – academician. RAMS (Moscow) M. M. Ilkovich – Doctor of Medical Sciences, Prof.

B. I. Tkachenko – academician RAMS (St. Petersburg) A. I. Krylova – Ph.D., Associate Professor G. B. Fedoseev – member. corr. RAMS (St. Petersburg) N. G. Neznanov – Doctor of Medical Sciences, Prof.

I. S. Freidlin – member. corr. RAMS (St. Petersburg) N. N. Petrishchev – Doctor of Medical Sciences, Prof.

N. A. Yaitsky – academician RAMS (St. Petersburg) Yu. S. Polushin – Doctor of Medical Sciences, Prof. E. S. Gabrielyan – academician (Yerevan) M. G. Rybakova – Doctor of Medical Sciences, Prof. V. N. Gurin – academician BAN (Minsk) S. A. Simbirtsev – doctor of medical sciences, prof. G. G. Lezhava – prof. (Tbi

– – –

Editor L. A. Aleksina Cover and art design E. V. Kornilova Computer layout and preparation of the original layout A. A. Chirkova Proofreader V. A. Chernikova

Reviews and lectures..,..,..

NUTRITIONAL AND METABOLIC THERAPY IN TRANSPLANT PATIENTS

HEMAPOIETIC STEM CELLS

Health care organization..

EXPERIENCE OF WORKING OF AN ADVISORY DIAGNOSTIC AND PREVENTIVE CENTER

FOR ADOLESCENTS WITH CHRONIC VIRAL INFECTIONS

MANAGEMENT OF MATERIAL AND TECHNICAL RESOURCES AS A NECESSARY CONDITION

PROVIDING QUALITY MEDICAL CARE

..,..,..,..,..,..

IMPLEMENTATION OF NEW ORGANIZATIONAL TECHNOLOGIES AS A CONDITION OF INCREASE

QUALITY OF MEDICAL CARE

ORGANIZATION OF SPECIALIZED MEDICAL CARE FOR CHILDREN WITH MAXILLARY

FACIAL PATHOLOGY (CLINICAL STATISTICAL ANALYSIS)

PERSONNEL PROBLEMS IN THE MATERNITY SERVICE

Original works..,..,..,..

INFLUENCE OF PHYTOTHERAPY ON THE STATE OF INFLAMMATION MARKERS IN ATHEROSCLEROSIS

BRACHEOCEPHAL ARTERIES

ROLE OF DETERMINING THE COEFFICIENT OF ADENOSINE DEAMINASE IN ETIOLOGICAL

DIAGNOSTICS OF PLEURITIS

INFLUENCE OF LIGHT IN THE OPTICAL RANGE ON THE DECOMPOSITION OF S NITROSOGLUTATHIONE.... 38

DIAGNOSTIC VALUE OF STUDYING TUMOR NECROSIS FACTOR AND RECIPES

THOROUGH ANTAGONIST OF INTERLEUKIN 1 IN LOCAL AND GENERALIZED

FORMS OF SOFT TISSUE INFECTION

..,..,..,..,..,..,..,..,..

THE IMPORTANCE OF DETECTING BRAF GENE MUTATIONS IN PREOPERATIVE CANCER DIAGNOSIS

THYROID GLAND

GENETIC POLYMORPHISMS OF THE HEMOSTASIS SYSTEM IN MIGRAINE WITH AURA IN CHILDREN.... 48

..,..,..,..,..,.. -,..,..

NALTREXONE AS A MEANS OF INCREASING ADHERENCE TO ARV THERAPY IN PATIENTS

HIV INFECTION WITH CONCOMIENT HEROIN DRUG ADDICTION

..,..,..,..,..,..,..,..

STUDY OF THE INFLUENCE OF PROBIOTIC ESCHERICIA AND ENTEROCOCCIS

ON THE IMMUNE SYSTEM OF HEALTHY RATS

APPLICATION OF OSTEOSCINTIGRAPHY TO ASSESS METABOLISM IN BONE TISSUE

IN TUBERCULOSIS AND NON-SPECIFIC LESIONS OF LARGE JOINTS

BEFORE AND AFTER SURGICAL TREATMENT

CLINICAL NEUROLOGICAL DISORDERS AND THEIR CORRECTION IN CHILDREN WITH CONGENITAL DISORDERS

SPINAL DEVELOPMENTAL MALFORMATIONS AND DYSPLASTIC SCOLIOSIS

DISORDERS OF SECRETORY FUNCTION OF THE SMALL INTESTINE AND THEIR CORRECTION WITH ETHANOL

INTOXICATION IN THE EXPERIMENT

EXPRESSION OF TOTAL LEUKOCYTE ANTIGEN CD45 ON MOBILIZED (CD34+)

BLOOD STEM CELLS OF HEALTHY DONORS

ON THE ISSUE OF DIFFERENTIAL MORPHOLOGICAL DIAGNOSTICS OF PRIMARY

ADENOCARCINOMA OF THE LIVER

ANALYSIS OF THE CAUSES OF DEATH OF VICTIMS IN CASES ESTABLISHED BY EXPERTS

CAUSE OF EFFECT RELATIONSHIP

INHERITANCE OF THE FORMATION OF DERMATOGLYPHIC SIGNS ON THE FINGERS

AND LEGS IN FAMILY GROUPS

Brief messages..,..,..,..

ANALYSIS OF DERMATOGLYPHIC SIGNS OF RESIDENTS OF THE SOUTH OF RUSSIA

RESULTS OF MOLECULAR GENETIC TYPING OF SYSTEM FACTORS

HEMOSTASIS OF PATIENTS WITH RETINAL VEIN THROMBOSIS

POSSIBILITIES OF AUTOFLUORESCENT DERMATOSCOPE FOR AGE ASSESSMENT

CHANGES

..,..,..,..,..,..

NEW P369INS MUTATION IN THE CYP1B1 GENE IN A PATIENT WITH PRIMARY CONGENITAL

GLAUCOMA FROM ST. PETERSBURG

REVIEWS AND LECTURES

« »,

, NUTRITIONAL AND METABOLIC

, - SUPPORT, -, - (-, REVIEWS AND LECTURES

73. Szeluga. D. J. Energy requirements of parentally fed bone // Pediatr. Hematol. Oncol. 2003. Vol. 20.4.

marrow transplant recipients / D. J. Szeluga // J. Patenter. P. 265271.

Enteral. Nutr. 1985. Vol. 9. P. 139143. 78. Uderzo, C. Total parenteral nutrition and nutritional assessment

74. Tartarone, A. Role of parenteral nutrition in cancer patients in leukemic children undergoing bone marrow transplantation / undergoing high-dose chemotherapy followed by autologous peripheral C. Uderzo // Eur. J. Cancer. 1991. Vol. 27. P. 758762.

blood progenitor cell transplantation / A. Tartarone // Tumori. 79. Weisdorf, S. Total parenteral nutrition in bone marrow transVol. 91. P. 237240. plantation: a clinical evaluation / S. Weisdorf // J. Pediatr.

75. Taskinen, M. Skeletal muscle protein reserve after bone marrow Gastroenterol. Nutr. 1984. Vol. 3. P. 95100.

transplantation in children / M. Taskinen, U. M. Saarinen // Bone 80. Weisdorf, S. A. Graft versus host disease of the intestine:

Marrow Transplantation. 1996. Vol. 18. P. 937941. a protein losing enterophathy is characterized by fecal alpha-1-antiThomas, E. D. Technique for human marrow grafting / trypsin / S. A. Weisdorf // Gastroenterology. 1983. Vol. 85.

E. D. Thomas, R. Storb // Blood. 1970. Vol. 36. P. 507515. P. 10761081.

77. Uckan, D. Serum zinc and alkaline phosphatase values in 81. Ziegler, T. R. Glutamine supplementation in bn marrow transpediatric bone marrow transplantation patients / D. Uckan plantation / T. R. Ziegler // r. J. Ntr. 2002. Vol. 87. P. 915.

HEALTHCARE ORGANIZATION

3. - /.. //. 2005. 5.. 1925.

2007:... : 5.,.. /, 2008. 397. ? /.. // 4.,.. - -. 2006. 6.. 49.

SCIENTIFIC NOTES OF SPbSMU NAMED AFTER ACAD. I. P. PAVLOVA VOLUME XVI N02 2009

,. 3 HEALTH CARE ORGANIZATION

, 100 %, -,. - 7.7%;. LITERATURE, 1.,..

SCIENTIFIC NOTES OF SPbSMU NAMED AFTER ACAD. I. P. PAVLOVA · VOLUME XVI · N02 · 2009, -, -.

() -, LITERATURE 1.,..

(- HEALTHCARE ORGANIZATION

HEALTHCARE ORGANIZATION

, (%)

:

HEALTHCARE ORGANIZATION

0 29; 1 2 3 4 5 6 7 8 9 10 11 12

HEALTHCARE ORGANIZATION

. 16

RESEARCH RESULTS

AND THEIR DISCUSSION

() 9 9 (, 21 (31,3 %).

: SCIENTIFIC NOTES OF SPbSMU I.M. ACAD. I. P. PAVLOVA VOLUME XVI N02 2009

SCIENTIFIC NOTES OF SPbSMU NAMED AFTER ACAD. I. P. PAVLOVA · VOLUME XVI · N02 · 2009 10 17 (35.4%), 1115 7 (14.6%), 1620 4 (8.3%), 2125: “- 1 (2.1%) , 2630 1 (2.1%), 1 (2.1%);

1 (0.3%) 45; 47 (12.2%) 45, " 24 (32.4%), 1 (2.1%), 610 7 (14.9%), 1115 10 (21.3%), 1620 " - 6 (12 .8%), 2125 5 (10.6%), 2630 2 (4.3%), "11 (14.9%), " - 11 (23.4%); 2 5 (10.6%);

3 (0.8%) 1620 1 (33.3%), » 8 (10.8%). 2 (66.7%); 1 (0.3%) 610;

6 (1.6%) 23 1 (16.7%), 45 2 (33.3%), 610 1 (16.7%), 1115 1 (16.7%), 1 (16.7%) ); 3 (0.8%) 111 1 (33.3%), - 23 1 (33.3%), 45 1 (33.3%); CONCLUSION, - - REFERENCES 1 (0.3%) 111 ; 1.,.. -ATTENTION READERS!

"". SCIENTIFIC NOTES OF SPbSMU NAMED AFTER ACAD. I. P. PAVLOVA VOLUME XVI N02 2009

0.3,. CONCLUSIONS.

SCIENTIFIC NOTES OF SPbSMU NAMED AFTER ACAD. I. P. PAVLOVA VOLUME XVI N02 2009

NOTE FOR AUTHORS

« » -..,.

INFORMATION

() : MISCELLANEOUS 1..

.... ; 499-70-81 (634).

REGULATIONS FOR AUTHORS

The Record of the I.P.Pavlov St. Petersburg State Medical University (IPP-SPSMU Record), is the official journal of the I.P.Pavlov St.. Petersburg State Medical University (IPP-SPSMU). It publishes reports on a broad spectrum of medical and related issues, either fundamental or applied, as well as reviews and tutorials. The general criteria for publication of a manuscript submitted to the IPP-SPSMU Record, is novelty and significance in theoretical and/or practical aspects. High priority is given to a manuscript that had not been published elsewhere then as an abstract. A usual type of the manuscript is a Regular Article, which incorporates Introduction, Materials & Methods, Results, Discussion, and List of References. The analogous sections should be presented in a Short Communication type of an article. Review Articles, Lectures, and History of Medicine Articles should be agreed with the Editorial Office beforehand requested unless by the Editorial Board itself, or reported on and approved for publication at a regular meeting of the Scientific Board of the IPPSPSMU.

The Editorial Board assigns manuscripts to two external experts for reviewing. On the basis of the written reviews and the decision of the Editorial Board, a manuscript is to be either accepted or rejected; it can also be sent to the author (authors) for alterations in accordance with the reviewers comments.

The Editorial Board is authorized to publish the accepted manuscripts in such journal issues and contents sequences that are considered optimal for the Journal.

SCIENTIFIC NOTES OF SPbSMU NAMED AFTER ACAD. I. P. PAVLOVA VOLUME XVI N02 2009

MANUSCRIPT PREPARATION

A manuscript of a Regular Article should be printed in triplicate, double-spaced using 2.5 cm wide margins all around, and restricted to 10 A4 numbered pages. The space allotted should incorporate all sections of the manuscript, including the numbered, alphabetically arranged, and full (with titles in quotation) List of References. In the text, the references are given as figures in the square parentheses. Figures and/or photos are submitted on the separate sheets, with indication of their optimal place on the left margins of the text. Up to six single (912 cm) or two composite (1418 cm) halftone photos ready for PC-scanning are accepted, each one with a scale bar, markings (if necessary), and figure legends as well as magnifications and staining modes on a separate sheet. All illustrations should be identified on the back with figure number, running title of the paper, name of the first author, and an arrow indicating the top. Short Communication should not exceed four pages, with three single or one composite photos, ten quotations, and the arrangement as in a Regular Article. Style and length for the Review Articles, Lectures, and History of Medicine Articles are to be stipulated with the Editor before manuscript submission.

Manuscripts not conforming to the Regulations will be returned to the authors without assessment.

Title page The title page bears name(s) of author(s), title of the manuscript, institution(s) where the work was done, all addresses and signatures of the authors. On the bottom of the Title Page, a full name, persons duties, academic degree(s), affiliation, as well as address, phone, facsimile, and e-mail coordinates are placed as to the author to whom the Journal should communicate.

Summary On a separate sheet summary should be prepared, in 200 words or less, followed by up to six key words, in italics, on a separate line.

Disk Submission The disk (1.44 MB) file of all sections of the paper, except for photos, should accompany the manuscript prepared on PCIBM (not Apple Mackintosh) compatible computer. Include an ASCII version on the disc, together with the word-processed version.

MISCELLANEOUS

1. Title page, summary, any figures, and figure legends are not included in the space allotted to a manuscript, of either Regular Article or Short Communication type.

2. It is advisable for the contributors to return the revised and re-printed versions of the manuscripts, and also the approved galley proofs within two months and two weeks after receipt, respectively. Otherwise, publishing of the manuscripts can be delayed.

3. Author and reviewer royalties for papers published and revised in the IPP-SPSMU Record are not provided for.

4. The manuscripts rejected by the IPP-SPSMU Record are not to be returned to the contributors.

Similar works:

"Kabardino-Balkarian State University named after. Kh. M. Berbekova Faculty of Medicine Department of Faculty and Endoscopic Surgery Course of Traumatology, Orthopedics and...”

88 p. Materials published in this issue are divided into the following sections: Biological chemistry; Forensic medicine. Part one. Biological chemistry. Dedicated to the 150th anniversary of S. S. Salazkin Historical material
L. V. Galebskaya, I. G. Shcherbak. The contribution of Professor S. S. Salazkin to the formation and development of protein biochemistry
Original works
E. V. Ageeva, Yu. V. Frolova, N. G. Nikulcheva, A. D. Denisenko. Lipolysis of plasma triglycerides in patients with familial forms of dyslipoproteinemia
E. G. Vilenskaya, A. V. Tuaeva, A. M. Efremov, E. B. Dizhe, I. A. Lapikov, D. A. Mogilenko, S. V. Orlov, A. P. Perevozchikov. Effect of bacterial lipopolysaccharide on mouse apolipoprotein A-I gene expression
E. E. Larionova, A. D. Denisenko. Effect of modified low-density lipoproteins and high-density lipoproteins on macrophage apoptosis
T. F. Subbotina, M. O. Novak, Yu. V. Kartyshkina, A. S. Shchureva, M. A. Dumpis. Effect of fullerenol C60(OH)24 on the parameters of the hemostasis system in vitro
D. A. Tanyansky, I. A. Martynikhin, A. D. Denisenko. The course of metabolic syndrome and the relationship of its manifestations with the content of adipokines in patients with schizophrenia: results of comparison with a group of mentally healthy patients with coronary artery disease
T. S. Gurevich. The role of connective tissue dysplasia in the occurrence of mitral regurgitation during mitral valve prolapse in athletes
L. V. Galebskaya, I. L. Solovtsova, V. P. Faenkova, M. A. Solovyova, D. A. Ovchinnikov. Effect of blood plasma on the spectral properties of coproporphyrin III
Brief messages
T. A. Bogomaz, L. B. Piotrovsky, M. A. Dumpis, I. G. Shcherbak, L. V. Galebskaya. Fullerenol in the “blood serum - erythrocyte” system
I. L. Solovtsova, E. A. Vorobyov, I. A. Kurpas, M. A. Solovyova. Participation of some apoptotic mechanisms in radachlorin-initiated photohemolysis
V. P. Faenkova, I. L. Solovtsova, E. A. Vorobyov, A. D. Denisenko, L. V. Galebskaya. Study of the mechanism of transport of radachlorin by human blood plasma

Part two. Forensic Medicine. Dedicated to the 110th anniversary of the Department of Forensic Medicine and Law of St. Petersburg State Medical University named after. acad. I. P. Pavlova Historical material
O. D. Yagmurov. 110 years of the Department of Forensic Medicine and Law of St. Petersburg State Medical University named after Academician I. P. Pavlov
Health Organization
E. S. Naumov. Method for quality control of the activities of doctors - forensic experts
O. E. Amelekhina, P. N. Ryazanov
Organization of interaction between the forensic medical service and medical institutions in the implementation conditions national project"Health"
Original works
V. L. Popov, V. M. Karavaev. The influence of the circumstances of injury on the nature of fatal combined injury in children
V. L. Popov, O. A. Egorova. Peculiarities of expert characteristics of mandibular fractures complicated by post-traumatic osteomyelitis
G. N. Zarafyants, V. A. Basharin. Aspects of forensic medical diagnosis of combined poisonings with neurotropic poisons
D. A. Efimov. Features of the course of shockogenic mechanical injury against the background of alcohol intoxication
I. Yu. Salova, P. V. Stepanova. Forensic characteristics of fatal carbon monoxide poisonings in the Northwestern Federal District in 2005 - 2009.
L. V. Petrov, I. Yu. Salova. Characteristics of focal changes in the brain in acute carbon monoxide poisoning
M. G. Rybakova, I. A. Kuznetsova. Pathogenetic mechanisms of sudden cardiac death
O. D. Yagmurov, A. E. Safray, N. A. Kuznetsova. Practice of post-mortem forensic medical studies of corpses of HIV-infected people
R.V. Petrov. Identification of a person by individual characteristics of the sella turcica of the skull
O. O. Bolshakova, T. Kh. Yusipova, G. M. Nutfullina, I. A. Kuznetsova. Characteristics of morpho-functional parameters cordially- vascular system rats under experimental postmenopausal conditions
V. L. Sidorov, O. D. Yagmurov. Modern capabilities of quantitative ELISA methods and the results of their use in forensic practice
Teaching Issues
G. N. Zarafyants, O. D. Yagmurov. Features of teaching forensic medicine at St. Petersburg State Medical University named after. acad. I. P. Pavlova in accordance with the new state educational standard
O. D. Yagmurov, G. N. Zarafyants, A. I. Rusanova. Teaching the discipline “Jurisprudence” at St. Petersburg State Medical University named after. acad. I. P. Pavlova

Scientific and practical peer-reviewed journal

« Scientific notes St. Petersburg State Medical University named after academician I.P. Pavlov” is the official scientific journal of St. Petersburg State Medical University, publishing articles on problems of medical science, practice and teaching.

By the decision of the Higher Attestation Commission (HAC) of the Ministry of Education and Science of the Russian Federation, the journal “Scientific notes of St. Petersburg State Medical University named after. acad. I. P. Pavlova" included in the List of leading peer-reviewed scientific journals and publications published in the Russian Federation, which recommend the publication of the main results of dissertation research for the academic degrees of Doctor and Candidate of Sciences.

Current issue

REVIEWS AND LECTURES

9-19 29

35-41 21

47-53 16

Introduction. The methodology for objective express diagnostics of cardiovascular and respiratory synchrony depending on the manifestation of static spinal deformities is outlined. Approaches to simultaneous static and dynamic studies of postural balance and spiroarteriocardiorhythmography are discussed.

Goal of the work– determination of the mutual influence of parameters of cardiovascular and respiratory synchrony and indicators of static and dynamic postural balance.

Material and methods. An analysis of indicators of static and dynamic postural balance and indicators of cardiovascular and respiratory synchrony among a population without manifested signs of pathology from the studied body systems was carried out.

Results. Statistically significant correlations of static spinal deformity indicators were observed only with functional respiratory indicators. Indicators of cardiovascular and respiratory synchronization are more stable.

Conclusions. The lordotic variant, in contrast to the kyphotic and scoliotic variants of static spinal deformity, significantly affects the functional indicators of the respiratory system, as well as indicators of cardiovascular and respiratory synchrony. The balance of sagittal deformations correlates with functional indicators of the cardiovascular and respiratory systems, as well as with indicators of cardiovascular and respiratory synchrony. It is important to emphasize that in order to maintain cardiovascular and respiratory compliance in the most commonly diagnosed variants of static deformities (kyphotic and scoliotic), significant modifications in cardiovascular and respiratory regulation were observed much less frequently than in lordotic deformities.

54-60 17

Introduction. Every 10th skin tumor is melanoma, the treatment plan for which is influenced by the presence of tumor cells in the sentinel lymph node.

Target research – study of metastasis of skin melanoma to clinically negative regional lymph nodes.

Material and methods. Biopsies of regional lymph nodes from 60 patients with cutaneous melanoma were studied using histological, immunohistochemical, cytological and immunocytochemical methods.

Results. 5% of patients were diagnosed with stage melanoma in situ, 15% – T1, 28.3% – T2, 23.3% – T3, 28.3% – T4. With lymph outflow through 1 lymph collector, metastases in the sentinel lymph node (SLN) were identified in 51%, and through 2 lymph collectors - in 81.8% of cases. In 35.3% of cases, tumor cells affected a single lymph node, in 64.7% - 2 or more lymph nodes. Metastases in the SLN with the formation of a secondary tumor in T1 melanoma were observed in 11.1%, T2 – in 5.9%, T3 – in 21.4%, T4 – in 47.1% of studies. Accumulations of cluster-type cells or scattered melanoma cells in the SLN were observed in 22.2% in T1, 41.2% in T2, 42.9% in T3, and 35.3% in T4. With lymph outflow through 1 collector, melanoma metastases in non-sentinel lymph nodes (NSLNs) were detected in 24%, and through 2 collectors - in 44.4% of cases. Secondary changes in the SLN were noted in 16.7% of cases of lesions of a single SLN, in 31.8% of cases – lesions of 2 or more SLNs. In 69.2% of cases of secondary tumor formation and in 4.8% of the presence of clusters in the SLN, melanoma metastases were found in the removed SLN.

Conclusions. With increasing T of skin melanoma, the number of sentinel lymph nodes with reactive changes decreased, and their number with metastases increased. Metastatic damage to sentinel lymph nodes with lymph outflow through 2 lymph collectors into 2 or more SLNs and SLNs exceeded SLN damage with lymph outflow through 1 lymph collector into single lymph nodes. The use of the immunocytochemical research method made it possible to expand the pathomorphological verification of metastatic lesions of sentinel lymph nodes by 66.7%.

TO HELP THE PRACTITIONER

61-67 19

We describe a rare observation of a patient with probable transmissible encephalopathy (Creutzfeldt-Jakob disease), whose leading clinical feature was rapidly progressing speech impairment while maintaining motor and sensory functions. The diagnosis of Creutzfeldt-Jakob disease was confirmed by the clinical picture with rapid progression of the disease, neuroimaging (magnetic resonance imaging of the brain in FLAIR, DWI modes) and electroencephalography. Other possible causes of primary progressive aphasia were excluded.

68-73 20

Acute cerebellitis is a common inflammatory syndrome in the pediatric population, much less common in adults. No description of acute cerebellitis in adults, in particular associated with Crohn's disease, was found in the Russian-language literature available to us. In this case, acute hemicerebellitis was observed in a 45-year-old patient with a long history of Crohn's disease, who received Mesalazine as a basic therapy, and also underwent resection of the ileotransverse anastomosis and resection small intestine 2 months before the onset of neurological symptoms. The disease debuted with severe headache and left-sided cerebellar symptoms. Magnetic resonance imaging (MRI) revealed signs of severe edema of the left hemisphere of the cerebellum, weak leptomeningeal accumulation of contrast agent along the sulci, and impaired cerebrospinal fluid dynamics. Lumbar puncture was limited by the possibility of developing dislocation syndrome. After intravenous pulse therapy with Methylprednisolone, there was a complete regression of symptoms and a decrease in pathological changes during control MRI. Over the next year, there were no relapses of the disease; a single convulsive episode was noted during a change in the basic therapy for Crohn's disease to Adalimumab. In this case, most likely, the nature of the hemicerebellitis is immune-mediated, which is supported by a temporary relationship with an increase in the activity of Crohn's disease and a significant positive response to pulse corticosteroid therapy. It is known that inflammatory bowel diseases have many extraintestinal manifestations, including neurological ones. A possible common pathogenetic basis for systemic inflammatory and autoimmune diseases, such as Crohn's disease and autoimmune cerebellitis, in our case can be considered a disturbance in the composition of the microbiota of the gastrointestinal tract.

A patient with unstable angina was implanted with 2 everolimus-containing stents with a permanent polymer (Promus Premier) and a biodegradable polymer (Synergy). After 9 months, optical coherence tomography was performed with calculation of indicators.

774 Synergy stent struts and 701 Promus Premier stent struts were analyzed. When assessing the thickness of the formed neointima, no significant differences were obtained (p = 0.47). At the same time, a larger number of uncovered struts was detected in the Promus Premier stent compared to Synergy (1.14% versus 0%, p=0.002). The number of malposed uncovered strata is not statistically different (0.14 versus 0.13, p=1.00), the difference in the number of malposed covered strata approaches statistically significant (1.14 versus 0.26, p=0.0545).

According to the results of optical coherence tomography, no significant differences were obtained between the studied platforms when assessing late lumen loss. A larger number of uncovered struts in a stent with a permanent polymer was identified, which can be considered as a risk factor for the development of late coronary thrombosis.

ISSN 1607-4181 (Print)
ISSN 2541-8807 (Online)

6 years before the creation of Geropharm LLC, Alexander Anisimovich Skoromets had already successfully used Cortexin in his practice;
5 years before the creation of Geropharm LLC, Alexander Anisimovich’s wife Anna Petrovna widely and effectively used Cortexin in the treatment of children from the first days of life until the passport period;
4 years before the creation of Geropharm LLC, the son of Alexander Anisimovich, Taras Alexandrovich, achieved high results in neurosurgical treatment and rehabilitation of patients, prescribing Cortexin in the early postoperative period

This brief historical fragment of the activities of the world-famous neurologist shows the continuity of the activities of the pharmaceutical company "Geropharm", which gives us the right (with the permission of Alexander Anisimovich) to present on our website a brief historical background about Academician of the Russian Academy of Medical Sciences Alexander Anisimovich Skoromets, which we do with great pleasure.

Skoromets Alexander Anisimovich

Academician of the Russian Academy of Medical Sciences, Doctor of Medical Sciences, Professor, Honored Scientist of the Russian Federation, laureate of the State Prize of Moldova.

Born on March 28, 1937 in the village. Anastasyevka, Romensky district, Sumy region, Ukraine. Father - Skoromets Anisiy Ivanovich (1906 - 1984) and mother - Skoromets (Panaseiko) Efrosinia Terentyevna (1903 - 1979). Wife - Skoromets Anna Petrovna - professor of child neurology (born in 1963), son - Skoromets Taras Aleksandrovich, neurosurgeon, professor (born in 1963 from his first marriage with Skoromets Tamara Sergeevna (born 1936) and son - Skoromets Alexander Alexandrovich (born 2001).

After graduating with a diploma of commendation from the Artopolot seven-year school (the village of Anastasyevka, Sumy region), in 1951 he entered the Sumy paramedic-midwife school, which he graduated with honors in 1954 and without entrance exams was enrolled in the medical faculty of the 1st Leningrad Medical Institute named after. acad. I.P. Pavlova, who graduated in 1960 and was accepted into clinical residency at the department of nervous diseases of this institute. After completing clinical residency training in 1962, he worked as a neurologist at MSCh-42 in Krasnoyarsk -45 in the system of the Third Main Directorate of the USSR Ministry of Health. From 1964 to 1967 he studied full-time graduate school at the Department of Nervous Diseases with a course in medical genetics under the guidance of prof. D.K. Bogorodinsky in the 1st LMI named after. acad. I.P. Pavlova. In 1967, he successfully defended his thesis on the topic: “Clinic of ischemic conditions in the lumbosacral segments of the spinal cord” and was hired as an assistant at this department (1967 - 1970), then as an associate professor (1970-1974). In 1973 he defended his doctoral dissertation on the topic: “Ischemic spinal stroke (clinical and experimental study)" and was accepted to the position of professor of this department, and since 1975 he was elected head of the department of neurology and neurosurgery of the 1st LMI named after. acad. I.P. Pavlova (in 1994 renamed the St. Petersburg State Medical University named after academician I.P. Pavlov), where he has been working to the present time (more than 30 years). He received the academic title of professor in 1978, in 1995 he was elected corresponding member of the Russian Academy of Medical Sciences, and in 2002 - a full member (academician) of the Russian Academy of Medical Sciences. Since 1977 he has been working as the chief neurologist of Leningrad - St. Petersburg.

He has extensive experience teaching clinical neurology to students of the medical and dental faculties. Prepared and published jointly with prof. D.K. Bogorodinsky and A.I. Shvarev textbook “Guide to practical exercises in the Clinic of Nervous Diseases" (1977), which was translated into Spanish. In 1989, he published the first edition of the manual for neurologists “Topical diagnosis of diseases of the nervous system”, which was subsequently revised and expanded, and has already gone through 5 editions (together with professors A.P. Skoromets and T.A. Skoromets).

In 2005, he published the textbook “Nervous Diseases” for medical students.

Scientific interests concern experimental and clinical neurology and neurosurgery. He studied the vascular system of the spinal cord and for the first time identified two extreme variants of its structure: mainline and scattered. A classification of pathogenetic factors leading to impaired cerebrospinal circulation (lesions of the vascular system itself, compression of the vessels supplying the spinal cord and iatrogenic factors) has been developed. For the first time he identified the syndrome of pathogenic compensation of cerebrospinal circulation. A classification of the clinical picture of myeloischemia is proposed depending on the extent of ischemia along the diameter and length of the spinal cord, which can be assessed based on the clinical signs of the disease. For the first time, he identified and developed a method for studying the phenomenon of “arterial push” and “venous push” in vascular malformation in the spinal canal. He created a new chapter of clinical neurology - vascular diseases of the spinal cord (spinal angioneurology). Many works are devoted to spondylogenic lesions of the nervous system, tunnel neuropathies, demyelinating lesions of the nervous system, inherited neuromuscular diseases, lesions of the nervous system due to pathology of internal organs and endocrine glands. With his active participation, a domestic school of manual medicine was created in the USSR (1975 - 1990) and Russia (1990 - 2006), he was president of the All-Russian Association of Manual Medicine (1997-2005), and since 2005 - honorary president of this Association.

Actively performs social work - deputy. Chairman of the All-Russian Society of Neurologists, member of the editorial board of the Journal of Neurology and Psychiatry named after. S.S. Korsakov", "Neurological Journal", "Stroke. Russian edition”, “Manual therapy”, “Medical academic journal”, “Scientific notes of St. Petersburg State Medical University named after. I.P. Pavlova”, “Neuroimmunology”, “Vertebroneurology”, “Neurological Bulletin. Journal named after V.M. Bekhterev" and others.

Academician A.A. Skoromets created a neurological school: he trained more than 800 neurologists through internship and clinical residency; more than 55 candidate and 15 doctoral dissertations were defended under his scientific leadership. Published more than 600 scientific works, including 30 monographs, textbooks and manuals.

In 1993 he was awarded honorary title- Honored Scientist of the Russian Federation, “Honored Worker higher education Russia" (1997), and in 1998 - laureate of the State Prize of Moldova. He was awarded the badge “Winner of the Socialist Competition of 1973”, “Excellence in Health Care” (1977), “For Excellent Achievements in Work” (in the field of higher education in the USSR, 1987), the medal “Veteran of Labor” (1989), “300 Years St. Petersburg" (2003), etc.

He is an honorary member of the Royal Medical Society of Great Britain, the European Society of Neurologists, the US Association of Neurologists, the Ukrainian Medical Academy, etc.
Academician A.A. Skoromets is active in charitable activities: in 1994 he organized the Prize Fund for excellent graduates of Anastasyevskaya high school(annual, by 2006, 31 gold and silver medalists became its laureates), in 1997 - a bonus fund for excellent students of Sumsky medical school(by 2005, more than 35 excellent graduates became its laureates), as well as at the St. Petersburg State Medical University. acad. I.P. Pavlova for young scientists for scientific works in the field of clinical and experimental neuroscience.

Scientific publications

D.K. Bogorodinsky, A.A. Skoromets Spinal cord infarctions. L. "Medicine", 1973. -224 p.
D.K. Bogorodinsky, D.G. German, O.O. Godovanik, A.A. Skoromets Spondylogenic lumbosacral radiculitis (typical and atypical complicated forms). Publishing house "Shtiintsa", Chisinau. 1975. - 144 p.
D.K. Bogorodinsky, A.A. Skoromets, A.I. Shvarev Guide to practical classes on nervous diseases. -M.: Medicine. - 1977. - 328 p.
D.G. Geroman, A.A. Skoromets Ischemic disorders of cerebral and spinal circulation (pathogenesis, clinical picture, treatment). -Chisinau, “Shtiintsa”, 1980, - 242 p.
D.G. German, A.A. Skoromets Disorders of the cerebrospinal circulation. - Chisinau, “Shtiinta”. 1981. - 282 p.
D.G. German, A.A. Skoromets Compressive radiculomedullary ischemia. -Chisinau, “Shtiintsa”, 1985, - 112 p.
D.G. German, A.A. Skoromets, M.V. Iretskaya Tunnel neuropathies. - Chisinau, “Shtiintsa”, 1989, - 239 p.
A.A. Skoromets Topical diagnosis of diseases of the nervous system. L. Medicine. 1989. - 315 p.
A.A. Skoromets, L.S. Sultanova, L.A. Ulitsky Neurological syndromes in disorders of carbohydrate metabolism. Ashgabat. 1990. - 160 p.
A.V.Amelin, Yu.D.Ignatov, A.A.Skoromets Migraine (pathogenesis, clinical picture and treatment). St. Petersburg Medical publishing house. 2001. - 200 p.
A.A.Skoromets, T.A.Skoromets Topical diagnosis of diseases of the nervous system. St. Petersburg :Polytechnic. 1996.- 320 pp., 3rd edition, 2000, - 398 pp.; 4th edition, 2002, - 398 p.
A.A. Skoromets, T.P. Thiessen, A.I. Panyushkin, T.A. Skoromets Vascular diseases of the spinal cord. Guide for doctors. SPb.: SOTIS. 1998, - 528 p., 2002, - 528 p.
A.A.Skoromets pr. A short reference book for a neurologist. SPb: SOTIS, 1999, - 352 p., 2002 - 352 p.
S.V.Mozhaev, A.A.Skoromets, T.A.Skoromets Neurosurgery. Textbook for students. St. Petersburg, 2001. - 356 p.
A.A. Skoromets, A.P. Skoromets, T.A. Skoromets, T.P. Thiessen Spinal angioneurology. Guide for doctors. M.: “MEDpress-inform”, 2003. - 608 p.
A.A.Skoromets, A.P.Skoromets, T.A.Skoromets Topical diagnosis of diseases of the nervous system. SPb.: Polytechnic. 5th edition. 2004. - 400 p.
I.M.Barbas, A.A.Skoromets Treatment of multiple sclerosis. St. Petersburg , 2004. - p. 131
Zavalishin I.A., Gusev E.I., Yakhno N.N., Skoromets A.A., Totolyan N.A. and others. Results of a multicenter study of the effectiveness of Rebif-22 mcg in Russia. In the book. Materials of the workshop “Organization of specialized medical care for patients with multiple sclerosis", October 9-11, 2003, Tomsk. - p.40 - 44
Skoromets A.A., Stolyarov I.D., Petrov A.M. HP All-Russian Conference “Neuroimmunology” and scientific and practical conference of neurologists. Right there. - p.55 - 58
Prahova L.N., Ilves A.G., Kataeva G.V., Petrov A.M., Skoromets A.A., Totolyan N.A., Stolyarov I.D. The use of positron emission tomography to assess the state of the gray matter of the brain in patients with multiple sclerosis. There, - p. 58 - 64
Amelin A.V., Skoromets A.A., Gonchar M.A., Tumelevich B.Ch., Nikitin K.A. Comparative effectiveness of betaserc and cinnarizine in the treatment of dizziness in patients with migraine. Journal of Neurology and Psychiatry. S.S. Korsakov. 2003.T.103., No. 5. - With. 43 - 48
Skoromets A.A., Nikitina V.V., Zhloba A.A. The effect of reamberin on the antioxidant activity of blood plasma in IN VITRO donors. Scientific notes of St. Petersburg State Medical University named after. acad. I.P. Pavlova, 2003. vol. X, No. 1. - P. 44 - 47
Skoromets T.A. The use of cortexin in patients with secondary ischemic disorders in acute period traumatic brain injury. Terra Medica. Application "Cortexin".2003. No. 1. -S.4 - 5
Skoromets A.A. Appeal to readers. Regional blood circulation and microcirculation. 2003, No. 2 (5), - P. 4
Subbotina N.S., Dudanov I.P., Skoromets A.A. Hemodynamic characteristics of stenotic lesions of extracranial segments of the carotid arteries in ischemic brain disease. Right there. - P. 15 - 20
Totolyan N.A., Trofimova T.N., Skoromets A.A., Tyutin L.A., Pozdnyakov A.V., Tychkova I.K. Possibilities of magnetic resonance imaging methods in the diagnosis of multiple sclerosis. Journal of Neurology and Psychiatry. S.S. Korsakov. Special issue. Multiple sclerosis. 2002. No. 1.-P.32-42
Ilves A.G., Prahova L.N., Kataeva G.V., Rudas M.S., Totolyan N.A., Skoromets A.A., Stolyarov I.D. Changes in brain glucose metabolism in patients with multiple sclerosis and their role in the formation clinical picture and in the progression of the disease. Journal of Neurology and Psychiatry. S.S. Korsakov. Special Issue 2 “Multiple Sclerosis.” Appendix to the magazine. 2003. - pp. 53-60
Nikitina V.V., Skoromets A.A., Barbas I.M., Yantareva L.I., Pospelova M.L. Diagnostic capabilities of neurophysiological methods for multiple sclerosis and acute demyelinating polyneuropathy. Right there. 2003. - P.68 - 69
Zavalishin I.A., Gusev E.I., Skoromets A.A., Totolyan N.A. and others. Results of a multicenter study of the effectiveness of the drug Rebif-22 mcg in Russia. Ibid., 2003. - P. 73 - 78
Skoromets A.A., Kovalchuk V.V. Analysis of the effectiveness of various medicines in the treatment of strokes. In the book. Actovegin in neurology. M., 2002. - P. 152 - 164
Skoromets A.A., Radchenko V.G., Fedorets V.N. Meaning behavioral characteristics in the treatment of patients with coronary disease hearts. Journal of Neurology and Psychiatry. S.S. Korsakov. 2003. T.103, issue 6. - P.47 - 49
Skoromets A.A., Monroe P., Sorokoumov V.A., Kamaeva O.V., Golikov K.V., Borisov A.V., Boricheva L.M., Kalyuta V.A., Zhelvakova L.Ya. . New treatment strategy for cerebral strokes: experience of a department for stroke patients in St. Petersburg. Journal of Neurology and Psychiatry. S.S. Korsakov. 2003, vol. 103, issue 9. Stroke. Appendix to the magazine. -P.56 - 61
Multidisciplinary approach to the management and early rehabilitation of neurological patients. Toolkit. Ed. A.A.Skoromets.
Part 1. Multidisciplinary approach. Organization of a stroke block. St. Petersburg 2003. - 34 p.
Part 2. Nursing issues. St. Petersburg, 2003. - 41 p.
Part 3. Speech therapy. Swallowing. St. Petersburg 2003. - 25 p.
Part 4. Function of the pelvic organs. St. Petersburg 2003. - 22 s
Part 5. Physical therapy. St. Petersburg, 2003. - 42 p.
Part 6. Occupational therapy. St. Petersburg 2003. - 40 p.
A.A.Sergeeva, A.A.Skoromets, A.V.Sergeev, A.T.Balashov, N.A.Matyushkin, A.V.Trifonov. Movement disorders in tick borne neuroinfections. European Journal of Neurology. 2004, September, vol. 11, supplement 2. - p. 320
Zvartau M.E., Kaon K., Lisak R.F., Kan O.A., Skoromets A.A. Comparative evaluation of immunomodulatory drugs for the treatment of relapsing-remitting multiple sclerosis. Journal of Neurology and Psychiatry. S.S. Korsakov. 2004. Volume 104. Issue. 7. -P.66 - 71
Totolyan N.A., Skoromets A.A. Treatment of multiple sclerosis in children and adolescents with beta-interferon drugs. Journal of Neurology and Psychiatry. S.S. Korsakov. 2004. volume 104. Issue. 9. - pp. 23 - 31
Volkova E.A., Skoromets T.A. Analysis of binocular and monocular optosensory processes in alternating concomitant strabismus using cognitive visual evoked potentials (CVEPs). Scientific notes. St. Petersburg 2004, vol. X1, no. 2. - P.79 - 80
V.I. Guzeva, A.A. Skoromets. Medical and social aspects of childhood epilepsy. In the book: International conference “Epilepsy - medical and social aspects. Diagnostics and treatment". M., 2004. - pp. 148-151
39. Skoromets A.A. A new strategy in the treatment of patients in the acute phase of cerebral stroke. Right there. - P.49 - 50
Grigorenko G.A., Zybina N.N., Fedorova N.V., Tishkovskaya Yu.N., Shestakova S.A., Skoromets A.A. Oxidative stress and antioxidant defense systems in the brain tissue of animals with experimental diabetes mellitus. Abstracts of reports of the Second Diabetes Congress “Diabetes Mellitus and Cardiovascular Complications.” Moscow. 2002. p.289
Grigorenko G.A., Zybina N.N., Shestakova S.A., Skoromets A.A., Fedorova N.V., Tishkovskaya Yu.N. Effect of alpha-lipoic acid on antiradical activity in brain tissue of rats with experimental diabetes mellitus. In the book: Psychopharmacology and biological narcology. 2002. No. 2-3, -p. 381 (Materials All-Russian Conference“Neuropharmacology in the 21st century”, dedicated to the 100th anniversary of academician S.V. Anichkov).
Grigorenko G.A., Barantsevich E.R., Melnikova E.V., Nikitina V.V., Skoromets A.A. Effect of recombinant superoxide dismutase on electrophysiological parameters of peripheral nerves in experimental diabetes. Actual problems modern endocrinology. Materials of the IV All-Russian Congress of Endocrinologists. St. Petersburg 2001. - P. 64
Melnikova E.V., Grigorenko G.A., Makhova O.A., Alexandrova L.A., Barantsevich E.R., Skoromets A.A. The effectiveness of lipoic acid in neurological complications diabetes mellitus. Cytology. 1999. T.41, No. 9. -WITH. 822 (Abstracts of reports and messages of the international conference “Free radical processes: environmental, pharmacological and clinical aspects”. St. Petersburg, 1999)
Barantsevitch E.R., Grigorenko G.A., Melnikova E.V., Skoromets A.A., Stepanov R.P., Shestakova S.A. Protective effect of ESPA-lipon in brain tissue in experimental diabetes mellitus. Pathophysiology. 1998. vol.5 (Suppl.1), -p.345 (III International Congress of Pathophysiology. Abstract book).
Barantsevich E.R., Alexandrova L.A., Grigorenko G.A., Melnikova E.V., Skoromets A.A. Neurometabolic drugs in the treatment of diabetic lesions of the nervous system. In the book: Metabolic therapy in cardiology, endocrinology and neurology. Proceedings of the international symposium. St. Petersburg 1998. - p.12.
S.V. Perfilyev, A.A. Skoromets Treatment of patients with spondylogenic neurological pain syndromes with large doses of dexamethasone. In the book: Modern trends in the diagnosis, treatment and prevention of diseases. St. Petersburg 2004. -P.110-118.
A.A.Skoromets Improving the quality of life in Parkinson's disease. M.2004. - 25 s. (brochure)
Skoromets A.A., Sandler B.I., Zevakhin S.V. Dynamics of C-reactive protein in the treatment of patients with lumbar disc herniations using puncture multichannel laser disc vaporization. Clinical and laboratory consultation (journal). 2004, No. 5, -P.32 - 34
Diseases of the nervous system. Guide for doctors. Edited by N.N. Yakhno. 4th ed. M. “Medicine”, 2005. vol. 1 and vol. 2. Chapter 3. Circulatory disorders in the brain and spinal cord. I.V.Damulin, V.A.Parfenov, A.A.Skoromets, N.N.Yakhno
Volchkov V.A., Skoromets A.A., Strashnov V.I., Sorokoumov V.A. The use of epidural blocks in the treatment of lumbar discogenic radiculitis. Medical academic journal. -2003. - T.3, No. 1. - p.77-83
Volchkov V.A., Strashnov V.I., Skoromets A.A., Sorokoumov V.A. Epidural blockades in the treatment of lumbar discogenic radiculitis. Abstract of the report Siberian interregional scientific and practical Conferences “Pain and palliative care. Novosibirsk 2002. - p.206-208
Dambinova S.A., Khunteev G.A., Zavolokov I.G., Skoromets A.A. Glutamate, homocysteine and antibodies to NMDA receptors as potential biomarkers of cerebral ischemia. In the book: Advances in functional neurochemistry. Edited by prof. S.A. Dambinova, academician of the Russian Academy of Natural Sciences, prof. A.V.Harutyunyan. From St. Petersburg University, 2003 - p. 363 - 379
Ilyukhina A.Yu., Skoromets A.A. Diagnostic significance of changes in the level of autoantibodies to NMDA-type glutamate receptors in the acute period of cerebral stroke. In the book: ibid. - P. 380 - 389
Khilko V.A., Skoromets A.A., Khachatryan V.A., Shuleshova N.V., Khilko G.I. Tumors of the brain stem. Hippocrates. 2005. - p. 504
Radchenko V.G., Skoromets A.A., Fedorets V.N. Patent for invention No. 2240838 “Method for preventing recurrent myocardial infarction in persons with behavioral type A.” Invention priority July 15, 2003 Patent expires July 15, 2023
Suslina Z.A., Rumyantseva S.A., Fedin A.I., Tanashyan M.M., Skoromets A.A., Nikitina V.V. and others. Clinical effectiveness of cytoflavin in dyscirculatory encephalopathy - chronic cerebral ischemia (results of a multicenter randomized trial). Bulletin of the St. Petersburg State Medical Academy named after. I.I.Mechnikov. Encephalopathy. 2005. No. 3 (6), -S. 7 - 14
Fedin A.I., Rumyantseva S.A., Piradov M.A., Skoromets A.A., Parfenov V.A., Klocheva E.G., Sholomov I.I. et al. Efficacy of the neurometabolic protector cytoflavin in cerebral infarctions (multicenter randomized trial). Bulletin of the St. Petersburg State Medical Academy named after. I.I.Mechnikova.Stroke. 2005. No. 1 (6), -S. 13 - 19
Agafina A., Kovalenko A., Rumyantseva S., Skoromets A., Klocheva E., Suslina Z., Kukhtsevich I., Sholomov I., Belonogov M. Efficacy of the neurometabolic protector cytoflavin in patients with ischemic stroke. In the early recovery period (multicenter randomized trial). Doctor. 2006. No. 1, -S. 1-4
A.A.Skoromets, A.P.Skoromets, T.A.Skoromets Propaedeutics of clinical neurology. SPb: Polytechnic. 2004., - 322 p.
Skoromets A.A., Skoromets A.P., Skoromets T.A. Nervous diseases. Tutorial. M., “MEDpress-inform”, 2005. - 544 p.
Skoromets A.A., Sandler B.I., Zevakhin S.V. Dynamics of the immune status of patients treated with puncture laser vaporization of lumbar disc herniations. Neuroimmunology. 2005. vol. 3, no. 1, - P. 51 - 54
Sergeev A.M., Skoromets A.A., Sergeeva A.A., Kovalenko A.I., Bondarenko G.E. Tick-borne neuroinfections in the Republic of Karelia. Neuroimmunology. 2005. vol. 3, no. 2.-S. 18
Vereshchagina I.V., Totolyan N.A., Skoromets A.A., Darskaya E.I., Afanasyev B.V. Experience of hematopoietic stem cell transplantation in the treatment of patients with multiple sclerosis at St. Petersburg State Medical University named after. I.P. Pavlova. Right there. - P.97
Tyutenok S.N., Vereshchagina I.V., Petrov A.M., Stolyarov I.D., Afanasyev B.V., Skoromets A.A. Experience with autologous transplantation of peripheral blood stem cells (PBSC) for multiple sclerosis (MS). Right there. - P. 109
Granstrem O.K., Walter Adriani Giovanni Laviola, Khunteev G.A., Shumilina M.V., Skoromets A.A. Morphine injections alter the balance between glutamate and opiate receptor antibody levels in rats. Right there. - P.162
Lokhov M.I., Skoromets A.A., Fesenko Yu.A. Possibilities early diagnosis minimal brain dysfunction (MBD) in children 2-7 years old according to the results of computer analysis of EEG. Scientific notes of St. Petersburg State Medical University named after. acad. I.P. Pavlova. 2005. T.12, No. 3. - P.87-91
Lokhov M.I., Skoromets A.A., Fesenko Yu.A. Delayed development of functional interaction between the structures of the cerebral cortex as the basis for the pathogenesis of speech disorders childhood(diagnosis and therapy). Review of Psychiatry and Medical Psychology named after. V.M. Bekhtereva. 2005. No. 4. - P. 10-13
A.A.Skoromets Development of manual medicine in the USSR and Russia. Manual therapy. Scientific and practical journal. 2005. No. 3 (19). - pp. 17-18
Matveev A.K., Vakharlovsky V.G., Totolyan N.A., Skoromets A.A. Late diagnosis of hepatolenticular degeneration (HLD). Medical genetics. 2005. vol.4, no.5.-P.227
S.A.Dambinova, A.A.Skoromets Differentiating Ischemic Stroke from Hemorrhage by Biomarkers. In: Program Book and Syllabus/ 4th International Conference on Biochemical Markers for Brain Damage. September 8-10, 2005. Maine, USA. - p. 53-57
Dambinova S.A., Izykenova G.A., Granstrem O.K., Skuliabin D.I., Skoromets A.A. Rapid blood test detecting AMPA receptor peptide for assessment of brain-related seizures. Ibid. - p.146
Sergeev A.M., Skoromets A.A., Sergeeva A.A. Treatment of tick-borne encephalitis with intravenous immunoglobulin. European Journal of Neurology. 2005, vol. 12, Suppl. 2. - p. 80

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